Glibenclamide Metformin is a combination of two antidiabetic medicines Glibenclamide and Metformin. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver delaying glucose absorption from intestines and increasing the body sensitivity to insulin.

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